Review



plasma hmgb1 levels  (Cusabio)


Bioz Verified Symbol Cusabio is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 95
      Buy from Supplier

    Structured Review

    Cusabio plasma hmgb1 levels
    Elevated <t>HMGB1</t> Expression in MM cell lines and xenograft models. ( A ) Relative HMGB1 mRNA levels in MM cell lines (NCI-H2452 and MSTO-211H) compared to normal mesothelial cells (MeT-5A), determined by quantitative real-time PCR. ( B ) Representative Western blot images showing HMGB1 protein expression in MM cell lines (NCI-H2452 and MSTO-211H) and normal mesothelial cells (MeT-5A). ( C ) Representative images of tumors from the MM xenograft model established by subcutaneous injection of MSTO-211H cells into BALB/c nude mice. ( D ) Plasma HMGB1 levels measured by ELISA in xenograft model mice. **, p < 0.01; ***, p < 0.001.
    Plasma Hmgb1 Levels, supplied by Cusabio, used in various techniques. Bioz Stars score: 95/100, based on 96 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasma+hmgb1+levels/HMGB1/pmc12197314-74-0-13
    Average 95 stars, based on 96 article reviews
    plasma hmgb1 levels - by Bioz Stars, 2026-10
    95/100 stars

    Images

    1) Product Images from "HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy"

    Article Title: HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy

    Journal: Toxics

    doi: 10.3390/toxics13060448

    Elevated HMGB1 Expression in MM cell lines and xenograft models. ( A ) Relative HMGB1 mRNA levels in MM cell lines (NCI-H2452 and MSTO-211H) compared to normal mesothelial cells (MeT-5A), determined by quantitative real-time PCR. ( B ) Representative Western blot images showing HMGB1 protein expression in MM cell lines (NCI-H2452 and MSTO-211H) and normal mesothelial cells (MeT-5A). ( C ) Representative images of tumors from the MM xenograft model established by subcutaneous injection of MSTO-211H cells into BALB/c nude mice. ( D ) Plasma HMGB1 levels measured by ELISA in xenograft model mice. **, p < 0.01; ***, p < 0.001.
    Figure Legend Snippet: Elevated HMGB1 Expression in MM cell lines and xenograft models. ( A ) Relative HMGB1 mRNA levels in MM cell lines (NCI-H2452 and MSTO-211H) compared to normal mesothelial cells (MeT-5A), determined by quantitative real-time PCR. ( B ) Representative Western blot images showing HMGB1 protein expression in MM cell lines (NCI-H2452 and MSTO-211H) and normal mesothelial cells (MeT-5A). ( C ) Representative images of tumors from the MM xenograft model established by subcutaneous injection of MSTO-211H cells into BALB/c nude mice. ( D ) Plasma HMGB1 levels measured by ELISA in xenograft model mice. **, p < 0.01; ***, p < 0.001.

    Techniques Used: Expressing, Real-time Polymerase Chain Reaction, Western Blot, Injection, Clinical Proteomics, Enzyme-linked Immunosorbent Assay

    Effect of HMGB1 silencing on MM cell migration and invasion. Scratch wound healing assays showing the migration of MSTO-211H ( A ) and NCI-H2452 cells ( B ) treated with blank control, siRNA control, and HMGB1 siRNA at 0, 24, 48, and 72 h. Representative images and quantification of Transwell assays assessing invasion in MSTO-211H and NCI-H2452 cells ( C ) treated with blank control, siRNA control, and HMGB1 siRNA. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. black group; ## p < 0.01, ### p < 0.001 vs. siRNA control group.
    Figure Legend Snippet: Effect of HMGB1 silencing on MM cell migration and invasion. Scratch wound healing assays showing the migration of MSTO-211H ( A ) and NCI-H2452 cells ( B ) treated with blank control, siRNA control, and HMGB1 siRNA at 0, 24, 48, and 72 h. Representative images and quantification of Transwell assays assessing invasion in MSTO-211H and NCI-H2452 cells ( C ) treated with blank control, siRNA control, and HMGB1 siRNA. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. black group; ## p < 0.01, ### p < 0.001 vs. siRNA control group.

    Techniques Used: Migration, Control

    Effect of HMGB1 silencing and EP treatment on cell cycle arrest and apoptosis. Comparison of apoptosis in MSTO-211H ( A ) and NCI-H2452 ( B ) cells treated with blank control, siRNA control, and HMGB1 siRNA. Cell cycle distribution in MSTO-211H ( C ) and NCI-H2452 ( D ) cells treated with 0, 2.5, 5, and 10 mM EP. Apoptosis analysis of MSTO-211H ( E ) and NCI-H2452 ( F ) cells treated with 0, 2.5, 5, 10, and 20 mM EP. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control group; # p < 0.05, ## p < 0.01 vs. siRNA control group.
    Figure Legend Snippet: Effect of HMGB1 silencing and EP treatment on cell cycle arrest and apoptosis. Comparison of apoptosis in MSTO-211H ( A ) and NCI-H2452 ( B ) cells treated with blank control, siRNA control, and HMGB1 siRNA. Cell cycle distribution in MSTO-211H ( C ) and NCI-H2452 ( D ) cells treated with 0, 2.5, 5, and 10 mM EP. Apoptosis analysis of MSTO-211H ( E ) and NCI-H2452 ( F ) cells treated with 0, 2.5, 5, 10, and 20 mM EP. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control group; # p < 0.05, ## p < 0.01 vs. siRNA control group.

    Techniques Used: Comparison, Control

    Effect of TAK-242 and TLR4 siRNA treatment on HMGB1-TLR4 signaling pathway in MM cells. The mRNA expression of key molecules in the HMGB1-TLR4 signaling axis in MSTO-211H ( A ) and NCI-H2452 ( B ) cells treated with 0 and 100 μM TAK-242. The mRNA expression of key molecules in the HMGB1-TLR4 signaling axis in MSTO-211H ( C ) and NCI-H2452 ( D ) cells treated with TLR4 siRNA. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control group; # p < 0.05, ## p < 0.01, ### p < 0.001 vs. siRNA control group.
    Figure Legend Snippet: Effect of TAK-242 and TLR4 siRNA treatment on HMGB1-TLR4 signaling pathway in MM cells. The mRNA expression of key molecules in the HMGB1-TLR4 signaling axis in MSTO-211H ( A ) and NCI-H2452 ( B ) cells treated with 0 and 100 μM TAK-242. The mRNA expression of key molecules in the HMGB1-TLR4 signaling axis in MSTO-211H ( C ) and NCI-H2452 ( D ) cells treated with TLR4 siRNA. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control group; # p < 0.05, ## p < 0.01, ### p < 0.001 vs. siRNA control group.

    Techniques Used: Expressing, Control

    Effect of EP and TAK-242 treatment on MM xenograft model in vivo. ( A ) Representative images of mice and tumors after treatment treated with PBS, EP, or TAK-242. ( B ) Changes in body weight of mice over time after PBS, EP, or TAK-242 treatment. ( C ) Tumor volume measurements over time in mice treated with PBS, EP, or TAK-242. ( D ) Tumor weights in mice treated with PBS, EP, or TAK-242. ( E ) H&E staining of tumor tissues from PBS, EP, and TAK-242 treated groups. ( F ) Immunohistochemical staining showing HMGB1 expression in tumor tissues from the three treatment groups. ( G ) Plasma HMGB1 levels measured by ELISA in the three treatment groups. * p < 0.05.
    Figure Legend Snippet: Effect of EP and TAK-242 treatment on MM xenograft model in vivo. ( A ) Representative images of mice and tumors after treatment treated with PBS, EP, or TAK-242. ( B ) Changes in body weight of mice over time after PBS, EP, or TAK-242 treatment. ( C ) Tumor volume measurements over time in mice treated with PBS, EP, or TAK-242. ( D ) Tumor weights in mice treated with PBS, EP, or TAK-242. ( E ) H&E staining of tumor tissues from PBS, EP, and TAK-242 treated groups. ( F ) Immunohistochemical staining showing HMGB1 expression in tumor tissues from the three treatment groups. ( G ) Plasma HMGB1 levels measured by ELISA in the three treatment groups. * p < 0.05.

    Techniques Used: In Vivo, Staining, Immunohistochemical staining, Expressing, Clinical Proteomics, Enzyme-linked Immunosorbent Assay

    Related Articles

    Clinical Proteomics:

    Article Title: HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy.
    Article Snippet: Tumor sections were stained with hematoxylin and eosin (H&E) for morphological evaluation, and immunohistochemistry (IHC) was performed to assess HMGB1 (Abcam, Shanghai, China) and TLR4 (Abcam, Shanghai, China) expression. .. Plasma HMGB1 levels were quantified using a Mouse HMGB1 ELISA kit (Wuhan Huamei Cusabio Biotech Co., Wuhan, China). .. The animal experiments were approved by the Experimental Animal Ethics Committee of Zhejiang Academy of Medical Sciences.

    Article Title: HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy
    Article Snippet: Tumor sections were stained with hematoxylin and eosin (H&E) for morphological evaluation, and immunohistochemistry (IHC) was performed to assess HMGB1 (Abcam, Shanghai, China) and TLR4 (Abcam, Shanghai, China) expression. .. Plasma HMGB1 levels were quantified using a Mouse HMGB1 ELISA kit (Wuhan Huamei Cusabio Biotech Co., Wuhan, China). .. The animal experiments were approved by the Experimental Animal Ethics Committee of Zhejiang Academy of Medical Sciences.

    Enzyme-linked Immunosorbent Assay:

    Article Title: HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy.
    Article Snippet: Tumor sections were stained with hematoxylin and eosin (H&E) for morphological evaluation, and immunohistochemistry (IHC) was performed to assess HMGB1 (Abcam, Shanghai, China) and TLR4 (Abcam, Shanghai, China) expression. .. Plasma HMGB1 levels were quantified using a Mouse HMGB1 ELISA kit (Wuhan Huamei Cusabio Biotech Co., Wuhan, China). .. The animal experiments were approved by the Experimental Animal Ethics Committee of Zhejiang Academy of Medical Sciences.

    Article Title: HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy
    Article Snippet: Tumor sections were stained with hematoxylin and eosin (H&E) for morphological evaluation, and immunohistochemistry (IHC) was performed to assess HMGB1 (Abcam, Shanghai, China) and TLR4 (Abcam, Shanghai, China) expression. .. Plasma HMGB1 levels were quantified using a Mouse HMGB1 ELISA kit (Wuhan Huamei Cusabio Biotech Co., Wuhan, China). .. The animal experiments were approved by the Experimental Animal Ethics Committee of Zhejiang Academy of Medical Sciences.



    Similar Products

    plasma hmgb1 levels  (Cusabio)
    95
    Cusabio plasma hmgb1 levels
    Elevated <t>HMGB1</t> Expression in MM cell lines and xenograft models. ( A ) Relative HMGB1 mRNA levels in MM cell lines (NCI-H2452 and MSTO-211H) compared to normal mesothelial cells (MeT-5A), determined by quantitative real-time PCR. ( B ) Representative Western blot images showing HMGB1 protein expression in MM cell lines (NCI-H2452 and MSTO-211H) and normal mesothelial cells (MeT-5A). ( C ) Representative images of tumors from the MM xenograft model established by subcutaneous injection of MSTO-211H cells into BALB/c nude mice. ( D ) Plasma HMGB1 levels measured by ELISA in xenograft model mice. **, p < 0.01; ***, p < 0.001.
    Plasma Hmgb1 Levels, supplied by Cusabio, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasma+hmgb1+levels/HMGB1/pmc12197314-74-0-13
    Average 95 stars, based on 1 article reviews
    plasma hmgb1 levels - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier
    plasma human hmgb1 levels  (Cusabio)
    95
    Cusabio plasma human hmgb1 levels
    Elevated <t>HMGB1</t> Expression in MM cell lines and xenograft models. ( A ) Relative HMGB1 mRNA levels in MM cell lines (NCI-H2452 and MSTO-211H) compared to normal mesothelial cells (MeT-5A), determined by quantitative real-time PCR. ( B ) Representative Western blot images showing HMGB1 protein expression in MM cell lines (NCI-H2452 and MSTO-211H) and normal mesothelial cells (MeT-5A). ( C ) Representative images of tumors from the MM xenograft model established by subcutaneous injection of MSTO-211H cells into BALB/c nude mice. ( D ) Plasma HMGB1 levels measured by ELISA in xenograft model mice. **, p < 0.01; ***, p < 0.001.
    Plasma Human Hmgb1 Levels, supplied by Cusabio, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasma+hmgb1+levels/HMGB1/pm30853521-163-0-17
    Average 95 stars, based on 1 article reviews
    plasma human hmgb1 levels - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier

    Image Search Results


    Elevated HMGB1 Expression in MM cell lines and xenograft models. ( A ) Relative HMGB1 mRNA levels in MM cell lines (NCI-H2452 and MSTO-211H) compared to normal mesothelial cells (MeT-5A), determined by quantitative real-time PCR. ( B ) Representative Western blot images showing HMGB1 protein expression in MM cell lines (NCI-H2452 and MSTO-211H) and normal mesothelial cells (MeT-5A). ( C ) Representative images of tumors from the MM xenograft model established by subcutaneous injection of MSTO-211H cells into BALB/c nude mice. ( D ) Plasma HMGB1 levels measured by ELISA in xenograft model mice. **, p < 0.01; ***, p < 0.001.

    Journal: Toxics

    Article Title: HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy

    doi: 10.3390/toxics13060448

    Figure Lengend Snippet: Elevated HMGB1 Expression in MM cell lines and xenograft models. ( A ) Relative HMGB1 mRNA levels in MM cell lines (NCI-H2452 and MSTO-211H) compared to normal mesothelial cells (MeT-5A), determined by quantitative real-time PCR. ( B ) Representative Western blot images showing HMGB1 protein expression in MM cell lines (NCI-H2452 and MSTO-211H) and normal mesothelial cells (MeT-5A). ( C ) Representative images of tumors from the MM xenograft model established by subcutaneous injection of MSTO-211H cells into BALB/c nude mice. ( D ) Plasma HMGB1 levels measured by ELISA in xenograft model mice. **, p < 0.01; ***, p < 0.001.

    Article Snippet: Plasma HMGB1 levels were quantified using a Mouse HMGB1 ELISA kit (Wuhan Huamei Cusabio Biotech Co., Wuhan, China).

    Techniques: Expressing, Real-time Polymerase Chain Reaction, Western Blot, Injection, Clinical Proteomics, Enzyme-linked Immunosorbent Assay

    Effect of HMGB1 silencing on MM cell migration and invasion. Scratch wound healing assays showing the migration of MSTO-211H ( A ) and NCI-H2452 cells ( B ) treated with blank control, siRNA control, and HMGB1 siRNA at 0, 24, 48, and 72 h. Representative images and quantification of Transwell assays assessing invasion in MSTO-211H and NCI-H2452 cells ( C ) treated with blank control, siRNA control, and HMGB1 siRNA. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. black group; ## p < 0.01, ### p < 0.001 vs. siRNA control group.

    Journal: Toxics

    Article Title: HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy

    doi: 10.3390/toxics13060448

    Figure Lengend Snippet: Effect of HMGB1 silencing on MM cell migration and invasion. Scratch wound healing assays showing the migration of MSTO-211H ( A ) and NCI-H2452 cells ( B ) treated with blank control, siRNA control, and HMGB1 siRNA at 0, 24, 48, and 72 h. Representative images and quantification of Transwell assays assessing invasion in MSTO-211H and NCI-H2452 cells ( C ) treated with blank control, siRNA control, and HMGB1 siRNA. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. black group; ## p < 0.01, ### p < 0.001 vs. siRNA control group.

    Article Snippet: Plasma HMGB1 levels were quantified using a Mouse HMGB1 ELISA kit (Wuhan Huamei Cusabio Biotech Co., Wuhan, China).

    Techniques: Migration, Control

    Effect of HMGB1 silencing and EP treatment on cell cycle arrest and apoptosis. Comparison of apoptosis in MSTO-211H ( A ) and NCI-H2452 ( B ) cells treated with blank control, siRNA control, and HMGB1 siRNA. Cell cycle distribution in MSTO-211H ( C ) and NCI-H2452 ( D ) cells treated with 0, 2.5, 5, and 10 mM EP. Apoptosis analysis of MSTO-211H ( E ) and NCI-H2452 ( F ) cells treated with 0, 2.5, 5, 10, and 20 mM EP. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control group; # p < 0.05, ## p < 0.01 vs. siRNA control group.

    Journal: Toxics

    Article Title: HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy

    doi: 10.3390/toxics13060448

    Figure Lengend Snippet: Effect of HMGB1 silencing and EP treatment on cell cycle arrest and apoptosis. Comparison of apoptosis in MSTO-211H ( A ) and NCI-H2452 ( B ) cells treated with blank control, siRNA control, and HMGB1 siRNA. Cell cycle distribution in MSTO-211H ( C ) and NCI-H2452 ( D ) cells treated with 0, 2.5, 5, and 10 mM EP. Apoptosis analysis of MSTO-211H ( E ) and NCI-H2452 ( F ) cells treated with 0, 2.5, 5, 10, and 20 mM EP. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control group; # p < 0.05, ## p < 0.01 vs. siRNA control group.

    Article Snippet: Plasma HMGB1 levels were quantified using a Mouse HMGB1 ELISA kit (Wuhan Huamei Cusabio Biotech Co., Wuhan, China).

    Techniques: Comparison, Control

    Effect of TAK-242 and TLR4 siRNA treatment on HMGB1-TLR4 signaling pathway in MM cells. The mRNA expression of key molecules in the HMGB1-TLR4 signaling axis in MSTO-211H ( A ) and NCI-H2452 ( B ) cells treated with 0 and 100 μM TAK-242. The mRNA expression of key molecules in the HMGB1-TLR4 signaling axis in MSTO-211H ( C ) and NCI-H2452 ( D ) cells treated with TLR4 siRNA. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control group; # p < 0.05, ## p < 0.01, ### p < 0.001 vs. siRNA control group.

    Journal: Toxics

    Article Title: HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy

    doi: 10.3390/toxics13060448

    Figure Lengend Snippet: Effect of TAK-242 and TLR4 siRNA treatment on HMGB1-TLR4 signaling pathway in MM cells. The mRNA expression of key molecules in the HMGB1-TLR4 signaling axis in MSTO-211H ( A ) and NCI-H2452 ( B ) cells treated with 0 and 100 μM TAK-242. The mRNA expression of key molecules in the HMGB1-TLR4 signaling axis in MSTO-211H ( C ) and NCI-H2452 ( D ) cells treated with TLR4 siRNA. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control group; # p < 0.05, ## p < 0.01, ### p < 0.001 vs. siRNA control group.

    Article Snippet: Plasma HMGB1 levels were quantified using a Mouse HMGB1 ELISA kit (Wuhan Huamei Cusabio Biotech Co., Wuhan, China).

    Techniques: Expressing, Control

    Effect of EP and TAK-242 treatment on MM xenograft model in vivo. ( A ) Representative images of mice and tumors after treatment treated with PBS, EP, or TAK-242. ( B ) Changes in body weight of mice over time after PBS, EP, or TAK-242 treatment. ( C ) Tumor volume measurements over time in mice treated with PBS, EP, or TAK-242. ( D ) Tumor weights in mice treated with PBS, EP, or TAK-242. ( E ) H&E staining of tumor tissues from PBS, EP, and TAK-242 treated groups. ( F ) Immunohistochemical staining showing HMGB1 expression in tumor tissues from the three treatment groups. ( G ) Plasma HMGB1 levels measured by ELISA in the three treatment groups. * p < 0.05.

    Journal: Toxics

    Article Title: HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy

    doi: 10.3390/toxics13060448

    Figure Lengend Snippet: Effect of EP and TAK-242 treatment on MM xenograft model in vivo. ( A ) Representative images of mice and tumors after treatment treated with PBS, EP, or TAK-242. ( B ) Changes in body weight of mice over time after PBS, EP, or TAK-242 treatment. ( C ) Tumor volume measurements over time in mice treated with PBS, EP, or TAK-242. ( D ) Tumor weights in mice treated with PBS, EP, or TAK-242. ( E ) H&E staining of tumor tissues from PBS, EP, and TAK-242 treated groups. ( F ) Immunohistochemical staining showing HMGB1 expression in tumor tissues from the three treatment groups. ( G ) Plasma HMGB1 levels measured by ELISA in the three treatment groups. * p < 0.05.

    Article Snippet: Plasma HMGB1 levels were quantified using a Mouse HMGB1 ELISA kit (Wuhan Huamei Cusabio Biotech Co., Wuhan, China).

    Techniques: In Vivo, Staining, Immunohistochemical staining, Expressing, Clinical Proteomics, Enzyme-linked Immunosorbent Assay